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Parent Directory 28-Jan-2010 17:01 - gene-phylogeny/ 29-Jun-2007 11:12 - gene-homology/ 06-Jul-2007 11:30 - daphnia-genome-available2007.html 06-Jul-2007 14:39 4k environ-stress-genes/ 02-Sep-2007 19:00 - superfamilies/ 12-Feb-2008 14:45 - gene-duplicates/ 03-Mar-2008 13:47 - gene-structure/ 23-May-2008 21:39 - tile-expression/ 07-Mar-2009 13:18 -
The arthropod crustacean Daphnia pulex (better known as the water flea) is a unique emerging model organism, straddling the genome reach of vertebrate model organisms such as Mouse, insects such as Drosophila, and nematodes such as Caenorhabditis elegans.
Daphnia shares with C. elegans an interesting and rich gene structure and wealth of gene duplications. It has closest gene homology to the insects, Apis and Drosophila. However it has nearly as many unique or strong gene homologies to Mouse as to insects.
As a model organism for ecology and environmental research for centuries, Daphnia provides a genome-environment experimental model unlike any other, where its natural freshwater environments are readily mimicked in lab, and environmental stresses can be readily tested in large-scale genomic experiments.
A great example of this genome-environment connection comes from Daphnia's well known hemoglobin response, called into play as they rapidly turn blood-red when oxygen is depleted in their ponds. Among Daphnia's many gene duplications, we find a tandem cluster of 8 hemoglobin genes ( http://wfleabase.org/genome-summaries/gene-duplicates/).
Whether you work with human or vertebrate genomes, insects, worms or other eukaryotes, you will find many aspects of interest in comparing your genomes of interest to this first crustacean draft genome sequence.
The Daphnia pulex genome will be available on 2007/07/07, in public early access, with a grand opening scheduled between Fall 2007 and Spring 2008, which will include a Genbank genome submission and publications. These sequence data were produced by the US Department of Energy Joint Genome Institute in collaboration with the Daphnia Genomics Consortium.
This early access release is made available via
Scientists wanting to contribute to the open community-wide annotation project that is currently ongoing should visit http://dgc.cgb.indiana.edu